Combination chemotherapy for disseminated malignant melanoma

Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma.

BACKGROUND Malignant melanoma, one of the most aggressive of all skin cancers, is increasing in incidence throughout the world. Surgery remains the cornerstone of curative treatment in earlier stages. Metastatic disease is incurable in most affected people, because melanoma does not respond to most systemic treatments. A number of novel approaches are under evaluation and have shown promising r...

Electrochemotherapy for disseminated superficial metastases from malignant melanoma.

BACKGROUND The aim of the study was to determine predictive factors for effectiveness, toxicity and local disease control in patients with malignant melanoma treated with bleomycin-based electrochemotherapy (ECT). METHODS Electrochemotherapy was offered to patients with superficially disseminated melanoma metastases unsuitable for resection and unresponsive to chemotherapy. RESULTS Eighty-f...

Treatment of malignant pheochromocytoma with combination chemotherapy.

Three patients with rapidly progressive, disseminated malignant pheochromocytoma were treated with a combination chemotherapeutic regimen consisting of cyclophosphamide, vincristine, and dacarbazine in repeated 21- to 28-day cycles. All three patients had a marked decrease in blood pressure and an improvement in performance status within the first few cycles of treatment. At a follow-up of 6 to...

Experimental treatment of patients with disseminated malignant melanoma

Schiza, A. 2017. Experimental treatment of patients with disseminated malignant melanoma. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1382. 80 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-0107-5. Malignant melanoma (MM) is the deadliest skin cancer with an ever-increasing incidence. New treatments have improved the prognosis for patients...

New therapeutical approaches for the treatment of malignant Melanoma